scutellaria baicalensis common name

[103], An injection of 20mg/kg isolated wogonin appears to be more effective at reducing carrageenaan-induced paw edema (82.9%) than ibuprofen. Scutellaria: Family: Lamiaceae (alt.Labiatae) Subfamily: Scutellarioideae: Nomen number: 33424: Place of publication: Bemerk. Baicalein was also associated with improvements in neurogenesis, neuroblast proliferation, neurotrophin signaling pathway, walking and locomotor behaviors, and regulation of gene expression.61. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. Examine.com and its Editors do not advocate nutritional supplementation over proper medical advice or treatment and this sentiment will never be expressed through pages hosted under Examine.com. [3], Scutellaria baicalensis (400mg/kg of 29.6% baicalin) in combination with the anti-diabetic drug Metformin (500mg/kg) in diabetic rats noted that all three groups (either drug in isolation plus the combination) were equally effective in reducing blood glucose and triglycerides over four weeks although they appeared to be additive in increasing pancreatic insulin concentrations and antioxidant status. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Unknown effects during pregnancy [301]. Numerous studies have suggested this herb should be further examined for its potential utiliza… Baicalin has a long history of use in traditional Chinese medicine. [7], Scutellaria baicalensis shows moderate anti-inflammatory effects on LPS-induced macrophage activation, with the ethanolic root extract (8.53% baicalin) reducing nitric oxide production to 8.85% of control at 800µg/mL and 54.6% at 200µg/mL (outperformed only by Schizonepeta tenuifolia). for this page. Baicalin exhibited hepatoprotective actions in rats as well.64 Other uses of Baikal skullcap preparations include treatment of neonatal jaundice,65 marked antiulcerogenic actions,66 sores, swelling, boils, and diabetic problems.2, An in vitro study reported weak estrogenic activity associated with S. baicalensis.67, Five flavonoids derived from S. baicalensis were found to inhibit alpha-glucosidase activity in vitro. Baicalein appears to be a GABAA receptor agonist, with the glycoside (Baicalin) having no such effect. One case report described the successful treatment of psoriasis with a topical ointment containing S. baicalensis as well as Indigo naturalis and Cortex phellodendri. This activation of AMPK has been shown to be responsible for lipid and cholesterol lowering effects of baicalin.[34][33]. Baikal skullcap was included as an ingredient in several pharmaceutical combination preparations found in a second century AD tomb in northwestern China.2, Baikal skullcap is prescribed in China for fever, cough, GI, and urinary problems. [19], Baicalin appears to involve intestinal microflora for its metabolism into baicalein (via removal of the glucuronide group), as decreasing intestinal microflora alters the kinetics of the flavonoid. In spontaneously hypertensive rats (also a model for attention deficits thought to be related to altered dopamine transportation[84]) oroxylin A appears to improve attention[48][49] thought to be related to its ability to block the dopamine transporter.[49]. Medically reviewed by Drugs.com. [69], Oroxylin A is able to inhibit microglia activation (from LPS) in the concentration range of 10-100µM as assessed by nitric oxide secretion[70][71] is able to prevent STAT1 activation (70-85% inhibition at 50µM) without affecting NF-kB translocation, ultimately resulting in less secretion of inflammatory cytokines. manufacturers, food companies, and industry funders. If undergoing medical therapies, then consult with your respective Therapist or Health Care Professional about possible interactions between your Treatment, any Pharmaceuticals or Drugs being given, and possible nutritional supplements or practices hosted on Examine.com. Baikal skullcap may exert a protective effect in neurodegenerative diseases due to anti-inflammatory, antioxidant, and antiapoptotic effects.1, Baikal skullcap may be useful for the treatment of Alzheimer disease. This information relates to an herbal, vitamin, mineral or other dietary supplement. Scutellaria baicalensis (Chinese Skullcap) is a traditional chinese medicine for the purposes of cardiovascular and cognitive health as well as longevity. [46], Oroxylin A has shown an ability to block the dopamine transporter (DAT) in a manner similar to methylphenidate, albeit with less potency (similar potency of oroxylin A to atomoxetine). Get a monthly report summarizing studies in the health categories that matter specifically to you. Easily stay on top of the latest research. Habitats: Sandy and rocky places near the sea shore. (Lamiaceae) is a plant of the genus Lamiaceae, and its root is the main part used as a medicine. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils. VI. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Constituent baicalin inhibited reverse transcriptase activity in HTLV-Ι-infected cells, as well as the activity of purified reverse transcriptase from Moloney murine leukemia virus and Rous-associated virus type 2.50 Other flavones, such as isoscutellarein from S. baicalensis leaves, also showed anti-influenza virus activity in vitro.51 Isoscutellarein-8-methylether from S. baicalensis roots had effects against influenza A and B viruses, with results suggesting inhibition of the replication of A/Guizhou and B/Ibaraki viruses by inhibiting the fusion of viral envelopes with the endosome/lysosome membrane that occur in the early stage of the virus infection cycle.52, Another in vitro study found baicalein exerted antimicrobial effects against 11 different oral bacterial species. Range: E. Asia - China, Japan, Korea, Mongolia. Due to potential antiplatelet, anticoagulant, and profibronolytic effects of baicalein,58 it should be used with caution in patients taking any medications or supplements that can prolong bleeding time. [50] This is thought to underlie the attention promoting effects observed at 5-10mg/kg oroxylin A (injections) that had a potency similar to 2mg/kg methylphenidate in spontaneous alterations[49] while 1-5mg/kg was slightly less effective at reducing impulsiveness. Grassy slopes in higher elevations 1 meaning, 3 translations and more for Scutellaria baicalensis Georgi Baikal! Effect was not the same magnitude as that seen with tacrolimus P-glycoprotein was not determined to ensure the displayed! Continued therapy and updates updated, to include the most recently available clinical trial evidence and Review. 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